Fig. 2
From: Influences of donor and host age on human muscle-derived stem cell-mediated bone regeneration
Comparison of bone regeneration mediated by young and old donor LBMP2/GFP-transduced hMDSCs after transplantation in young animal hosts. a MicroCT 3D images of skull defect injury and new bone volume quantification using three pairs of young and old donor hMDSCs. b New bone volume was significantly higher when using old donor 1 cells compared to using young donor 1 cells at 4 and 6 weeks post-injury. c New bone volume was not significantly different between young donor 2 and old donor 2 cells at any time point. d New bone volume was significantly higher when using old donor 3 cells compared to using young donor 3 cells. e When results for all three old donor cells were combined and compared to combined results for all three young donor cells, new bone volume was significantly higher at 2, 4, and 6 weeks post-injury when old donor cells were transplanted. *P < 0.05, **P < 0.01