Table 2 Prognostic factors for lung SCC patients
From: miR-181b/Notch2 overcome chemoresistance by regulating cancer stem cell-like properties in NSCLC
Variables | HR | Univariate 95% CI | p | HR | Multivariate 95% CI | p |
|---|---|---|---|---|---|---|
OS | ||||||
Age (years) | ||||||
 ≤ 55 vs. > 55 | 1.002 | 0.965–1.039 | 0.932 |  |  |  |
Gender | ||||||
 Male vs. female | 0.309 | 0.110–1.868 | 0.076 |  |  |  |
Differentiation | ||||||
 Good/moderate vs. poor | 0.717 | 0.330–1.558 | 0.401 |  |  |  |
pT status | ||||||
 pT2–4 vs. pT1 | 3.747 | 1.721–8.160 | 0.001 |  |  | 0.580 |
pN stage | ||||||
 pN1–2 vs. pN0 | 3.090 | 1.569–6.086 | 0.001 |  |  | 0.180 |
pTNM stage | ||||||
 II–III vs. I | 4.921 | 2.629–9.210 | 0.000 | 5.744 | 1.908–17.290 | 0.002 |
miR181b expression | ||||||
 Low vs. high | 0.293 | 0.147–0.586 | 0.001 | 0.378 | 0.184–0.775 | 0.008 |
NOTCH2 expression | ||||||
 Low vs. high | 1.436 | 1.062–1.941 | 0.019 |  |  | 0.242 |
CD133 expression | ||||||
 Low vs. high | 1.229 | 0.776–1.945 | 0.380 |  |  |  |
SOX2 expression | ||||||
 Low vs. high | 1.013 | 0.718–1.430 | 0.939 |  |  |  |