Table 1 Experimental details of studies, mouse strains, cell types, route of administration, dose and number of animals studied

BLI short-term biodistribution (and MSOT for RAW macrophages)

BALB/c

mMSC

IV and IC

1.0 × 10⁶

Minimum n = 3 for each cell type and administration route

BALB/c

mKSC

IV and IC

1.0 × 10⁶

BALB/c

hUC-MSC

IV and IC

1.0 × 10⁶

BALB/c

hBM-MSC

IV and IC

5.0 × 10⁵

BALB/c

hKC

IV and IC

0.3 × 10⁵

BALB/c

Macrophages

IV and IC

1.0 × 10⁷

BLI long-term biodistribution

BALB/c SCID

mMSC

IV

1.0 × 10⁶

n = 3

BALB/c SCID

mMSC

IC

1.0 × 10⁶

n = 5

BALB/c

mMSC

IC

1.0 × 10⁶

n = 4

FVB

mMSC

IC

1.0 × 10⁶

n = 4

MF1

mMSC

IC

1.0 × 10⁶

n = 4

BALB/c SCID

hUC-MSC

IV

1.0 × 10⁶

n = 13

BALB/c SCID

hUC-MSC

IC

1.0 × 10⁶

n = 3

BALB/c SCID

hUC-MSC

IV

5.0 × 10⁵

n = 6

BALB/c SCID

hUC-MSC

IC

5.0 × 10⁵

n = 14

BALB/c SCID

hBM-MSC

IV

5.0 × 10⁵

n = 6

BALB/c SCID

hBM-MSC

IC

5.0 × 10⁵

n = 6

MRI cell tracking

BALB/c

mMSC

IV

1.0 × 10⁶

n = 2

BALB/c

mMSC

IC

1.0 × 10⁶

n = 7