Fig. 6

Systemic human iPS cell-derived iEPC therapy attenuated cardiac dysfunction after acute kidney injury (AKI). a Representative M-mode echocardiographic images of the left ventricles in mice before (Pre-AKI) or 2 days after AKI (Post-AKI). Mm (millimeter) indicates the depth of tissues. b–d Cardiac function parameters including cardiac output (CO), left ventricular ejection fraction (LVEF), and left ventricular fractional shortening (LVFS), as assessed using M-mode echocardiography. N = 6 per group. *P < 0.05 vs. Pre-AKI. e Plasma levels of brain natriuretic peptide (BNP). N = 5 per group. Data are expressed as mean ± SEM. *P < 0.05 AKI-V vs. Sham, ^#P < 0.05 AKI-iEPC vs. AKI-V group