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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Exosomes secreted by endothelial progenitor cells accelerate bone regeneration during distraction osteogenesis by stimulating angiogenesis

Fig. 4

EPC-Exos accelerated bone regeneration during distraction osteogenesis in rats. a Representative 3D micro-CT images of the tibial distraction zone after consolidation for 2 and 4 weeks indicated more continuous callus in the Exo-2 and EPCs group. b, c Quantitative analysis of micro-CT data showed higher values of bone mineral density (BMD) and bone volume/total tissue volume (BV/TV) in the Exo-2 and EPCs group. *P < 0.05, **P < 0.01, #P < 0.001 vs PBS group. EPCs endothelial progenitor cells, Exo exosomes secreted by EPCs, PBS phosphate-buffered saline

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Stem Cell Research & Therapy

ISSN: 1757-6512