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Table 3 SYRCLE risk of bias assessment for the included studies

From: Efficacy of stem cell therapy for pulmonary arterial hypertension: a systematic review and meta-analysis of preclinical studies

Author (year) Random sequence generation? Groups similar at baseline? Allocation concealed? Animals randomly housed? Blinding of caregivers and/or examiners? Random selection for outcome assessment? Blinding of outcome assessor? Incomplete outcome data addressed? Free from selective outcome reporting? Free from other bias?
Lim et al.(2016) [39] U L U U U U U L L L
Lee et al. (2017) [36] U L U U U U H L L L
Guo et al.(2013) [30] U L U U U U U L L L
Luan et al. (2012) [42] U L U U U U U L L L
Baber et al. (2006) [25] U L U U U U U L L L
Chen et al. (2014) [27] U L U U U U U L L L
Chen et al. (2016) [28] U L U U U U U L L L
Cheng et al. (2017) [29] U L U U U U U L L L
Huang et al. (2016) [31] U L U U U U U L L L
Chen et al. (2016) [26] U L U U U U U L L L
Jiang et al. (2012) [32] U L U U U U U L L L
Kang et al. (2015) [33] U L U U U U U L L L
Lee et al. (2015) [37] U L U U U U U L L L
Kim et al. (2012) [34] U L U U U U U L L L
Kim et al. (2016) [35] U L U U U U U L L L
Liang et al. (2015) [38] U L U U U U U L L L
Liu et al. (2015) [40] U L U U U U U L L L
Luan et al. (2013) [43] U L U U U U U L L L
Luo et al. (2014) [44] U L U U U U U L L L
Raoul et al. (2007) [45] U L U U U U U L L L
Rathinasabapathy et al. (2016) [46] U L U U U U U L L L
Somanna et al. (2014) [47] U L U U U U U L L L
Takemiya et al. (2009) [15] U L U U U U U L L L
Zhang et al. (2012) [49] U L U U U U U L L L
Zhang et al. (2012) [50] U L U U U U U L L L
Liu et al. (2011) [41] U L U U U U U L L L
Umar et al. (2009) [48] U L U U U U U L L L
Kanki et al.(2005) [14] U L U U U U U L L L
  1. H high risk of bias, L low risk of bias, U unclear risk of bias