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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Interaction with hyaluronan matrix and miRNA cargo as contributors for in vitro potential of mesenchymal stem cell-derived extracellular vesicles in a model of human osteoarthritic synoviocytes

Fig. 2

Characterization FLSs. a, b Representative FLS population at passage 0 (P0) and 1 (P1) shows the initial presence and steady reduction of CD14+ monocyte with enrichment of CD73+ events. c Synovial cells (CTRL) with added red blood cells to demonstrate clear pericellular zones. As control of HA coat involvement in erythrocyte exclusion, synovial cells pre-treated for 24 h with 4-MU to block HA coat synthesis are shown (4-MU). Bright field. d FLSs stained for CD73 surface marker shows thin lines representing cell protrusions

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