Fig. 3From: Differentiation of primordial germ cells from premature ovarian insufficiency-derived induced pluripotent stem cellsPOI-1-iPSCs differentiate into all three germs in vitro and in vivo. a POI-1-iPSCs were induced to express AFP. b POI-1-iPSCs were induced to differentiate into smooth muscle. c. POI-1-iPSCs were induced to differentiate into nerve cells. Teratoma formation indicated the existence of tissues from all three germ layers, such as d intestines (endoderm) (ectoderm), neural tube (ectoderm), e cartilage (mesodermal), and f adipose tissue (mesoderm), epidermal tissues and muscle (mesoderm)Back to article page