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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Elevated level of mitochondrial reactive oxygen species via fatty acid β-oxidation in cancer stem cells promotes cancer metastasis by inducing epithelial–mesenchymal transition

Fig. 5

Metabolic remodeling in RH-TS. a Heatmap of differentially expressed genes among parental cells, RH-TS cells, and RL-TS cells. b Expression changes of metabolic enzymes between RH-TS cells and RL-TS cells. * p < 0.05, ** p < 0.01, *** p < 0.001; unmarked, not significant. c A diagram depicting the changes in major metabolic pathways in RH-TS cells compared to RL-TS cells. Red objects and blue objects represent significant upregulation or downregulation in RH-TS cells, respectively. d The cytosolic free NAD/NADH ratio in RH-TS cells was significantly less than that in RL-TS cells. e Representative photographs of cell mitochondria by transmission electron microscopy

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Stem Cell Research & Therapy

ISSN: 1757-6512