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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Lineage-specific exosomes promote the odontogenic differentiation of human dental pulp stem cells (DPSCs) through TGFβ1/smads signaling pathway via transfer of microRNAs

Fig. 3

Endocytosis of OD-Exo by DPSCs triggered odontogenic differentiation. Endocytosis of OD-Exo isolated under odontogenic conditions triggered odontogenic differentiation of DPSCs by upregulating protein expressions of DSP, DMP-1, ALP, and RUNX2, when compared to control group (without exosomes) and UN-Exo group (p < 0.05). And DPSCs treated with UN-Exo only expressed higher protein level of DSP than the control group (p < 0.05), but no significant differences in DMP-1, ALP, and RUNX2

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