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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Apelin enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly through Wnt/β-catenin signaling pathway

Fig. 1

Endogenous Apelin expression and the influence of exogenous recombinant Apelin-13 on the proliferation and osteogenesis differentiation of hBMSCs. a–c Apelin expression level remained constant during osteogenic differentiation of hBMSCs. d hBMSC proliferation was examined by the CCK-8 assay. e–i hBMSCs were incubated with different concentrations (0–1000 nM) of Apelin-13 for 3 days. The expression of RUNX2 and COL1A1 were significantly upregulated by Apelin-13. All data are expressed as mean ± SD. Assays were performed in triplicate. *P < 0.05 and **P < 0.01 compared with the control group

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Stem Cell Research & Therapy

ISSN: 1757-6512