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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: SDF-1/CXCR4 axis enhances the immunomodulation of human endometrial regenerative cells in alleviating experimental colitis

Fig. 2

SDF-1 plays a crucial role in ERC-mediated generation of DC, M2, and Treg cells in vitro. a, b Splenocytes obtained from BALB/c mice were co-cultured with ERCs which were pretreated with or without SDF-1/AMD3100 and different stimulators for 96 h. The percentages of DCs (CD11c+MHCII+), M2 (CD68+CD206+), and Tregs (CD4+CD25+Foxp3+) were measured by flow cytometry. Sp indicated splenocytes. St indicated the corresponding stimulators. #ERCs indicated ERCs pretreated with SDF-1. *ERCs indicated inhibition the function of SDF-1 by AMD3100. The p value was determined by one-way ANOVA, n = 6. ***p < 0.001, **p < 0.01, *p < 0.05

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Stem Cell Research & Therapy

ISSN: 1757-6512