Fig. 6

Mitochondrial transfer from RA-sMSCs to CD4⁺ T cells is less efficient than that from BM-MSCs. a Representative histogram of mitochondrial transfer from synovium-derived MSCs (patients with rheumatoid arthritis; RA-sMSCs) and from BM-MSCs (healthy donors) to CD4⁺ T cells. b Quantification of the percentage of mitochondrial transfer from RA-sMSCs and from BM-MSCs to CD4⁺ T cells. Data are the mean ± SEM of at least 3 independent experiments using PBMCs from three donors and BM-MSCs from three healthy donors or RA-MSCs from three patients with RA (PBMC to BM-MSC or RA-sMSC ratio = 1:25)