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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Intraportally delivered stem cell spheroids localize in the liver and protect hepatocytes against GalN/LPS-induced fulminant hepatic toxicity

Fig. 2

3D-ADSC1000 rescued mice from GalN/LPS-induced lethal FHF. a Timeline of the study. b Survival curve of 1500 mg/kg GalN and 20 μg/kg LPS-treated BALB/c nude mice injected with PBS, 1 × 106 2D-ADSC, or 1000 3D-ADSC1000. Log-rank (Mantel-Cox) test was used to calculate the statistical significance. c Serum glutamic oxaloacetic transaminase (GOT) levels. d Serum glutamic pyruvic transaminase (GPT) levels. GPT and GOT were analyzed in the surviving mice via the colorimetric method using a chemistry analyzer. Data represent mean ± SEM. *p < 0.05, **p < 0.01, and ***p < 0.001

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