Fig. 2

Decitabine enhances the effects of UC-MSCs on improved insulin resistance. a–c HOMA-IR assessment of mice in each group at 1 week (a), 2 weeks (b), and 4 weeks (c) after treatment for systematic insulin resistance. HOMA-IR index = (FBG [in mmol/L] × FINS [in units/L])/22.5. d–f Immunoblotting analysis of p-AKT and total AKT expression in epididymal adipose tissue at 1 week (d), 2 weeks (e), and 4 weeks (f) after treatment. The ratios of p-AKT to total AKT were quantitated. Values are the means ± SD; n = 6 mice per group; *P < 0.05, **P < 0.01. p-AKT, phosphorylated AKT