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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Decitabine assists umbilical cord-derived mesenchymal stem cells in improving glucose homeostasis by modulating macrophage polarization in type 2 diabetic mice

Fig. 6

UC-MSCs combined with decitabine induced M2 macrophage polarization and activation of the IL-4R/STAT6/PPARγ pathway. a Immunoblotting analysis of macrophages from the Con, LPS + IFN-γ, MSC, DAC, and MSC + DAC groups. b–e Relative protein levels of IL-4R, p-STAT6, p-STAT3, and PPARγ are shown. Images of a are representative of three independent experiments. *P < 0.05; **P < 0.01

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