Fig. 4

Human PMSCs attenuated target proteins level in GO animal model. The resultant changes in a TSH-receptor, TGFβ1, TGFβ2, ICAM-1, and TNF-α and b general signaling involved proteins were examined by immunoblot analysis of GO mice orbital tissues. Expression levels were normalized to α-tubulin, and the quantified values of target proteins expression are also presented (down panel). Significantly different values between the groups are indicated with marks (*p < 0.05, **p < 0.005, ***p < 0.001 vs age-matched sham; ⁺p < 0.05, ⁺⁺p < 0.01, ⁺⁺⁺p < 0.001 vs intra-treatment groups). The red lines on the immunoblot data presented each group