Fig. 3

NLGP downregulates the secretion of inflammatory cytokines from TC-MSCs. MSCs and TC-MSCs were cultured in vitro in the presence or absence of NLGP for 48 h. Then, the cell-free supernatants, harvested from naive MSCs and TC-MSCs with or without NLGP treatment, were assessed for their content of a IL-6, b IL-10, c VEGF, and d TGFβ by ELISA (presented as mean ± SD values in pg/ml) using bar diagrams. Four independent experiments were performed. *p < 0.05, **p < 0.001 versus TC-MSC supernatant. ns = nonsignificant