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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Modulation of osmotic stress-induced TRPV1 expression rescues human iPSC-derived retinal ganglion cells through PKA

Fig. 2

Hyperosmotic stress responses of hiPSC-derived RGCs. a Morphology changes of hiPSC-derived RGCs treated with various concentrations of NaCl for 24 and 48 h. b Immunofluorescence staining of neurite markers Thy-1 and MAP2 of hiPSC-derived RGCs treated with various concentrations of NaCl for 48 h. c ImageJ-measured axon lengths of iPSC-derived RGCs treated with various concentrations of NaCl for 24 h. d Expression of cleaved caspase 3 determined by immunostaining in hiPSC-derived RGCs incubated in the indicated concentrations of NaCl for 48 h. e Quantification of expression of cleaved caspase 3 in hiPSC-derived RGCs treated the indicated concentrations of NaCl for 48 h. f Electrophysiological analysis of RGCs treated with the indicated concentrations of NaCl for 48 h

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Stem Cell Research & Therapy

ISSN: 1757-6512