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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Differentiation of adipose-derived stem cells to functional CD105neg CD73low melanocyte precursors guided by defined culture condition

Fig. 5

PreMel synthetize melanin and form melanosomes. a, b Representative cellular pellets of ADSC, PreMel, and HEM and quantification of the respective mean gray value. c Melanin content was determined in ADSC, PreMel, and HEM. Pigment is present in PreMel but is significantly lower than in HEM. *P < 0.05 unpaired Student’s t test and Welch’s correction. d–f Ultrastructural analysis shows representative melanosomes in the cytoplasm of PreMel and a higher magnification in the inset. White arrowheads show the single and double membrane of melanosomes and mitochondria, respectively. g–i Cytoplasmic HEM melanosomes. Scale bar = 250 μm

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Stem Cell Research & Therapy

ISSN: 1757-6512