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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Role of tissue factor in the procoagulant and antibacterial effects of human adipose-derived mesenchymal stem cells during pneumosepsis in mice

Fig. 3

Activation of the coagulation system induced by intravenous ASCs is dependent on ASC-associated tissue factor. Plasma concentrations of thrombin-antithrombin complexes (TATc) 3 h after intravenous infusion of 1 × 106 cryopreserved ASCs measured in uninfected mice and mice infected with K. pneumoniae via the airways 1 h prior to ASC infusion. ASCs were preincubated with a blocking anti-tissue factor antibody or isotype control prior to infusion. Data are expressed as bars (mean with SD), N = 4 mice per group. *p < 0.05 versus the control group

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