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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Mechanical process prior to cryopreservation of lipoaspirates maintains extracellular matrix integrity and cell viability: evaluation of the retention and regenerative potential of cryopreserved fat-derived product after fat grafting

Fig. 6

Regenerative potential of the cryo-gel in an ischemic wound healing model. a Gross appearance. PBS (control group), cryo-fat, or cryo-gel (0.1 cc each) was injected around the wound periphery. The cryo-gel accelerated the ischemic wound healing process, which was not observed with the cryo-fat. b Measurement of wound size. On day 8, the wound size in the cryo-gel group was significantly smaller than that in the other two groups, and a significant difference was still observed on day 10. The cryo-gel group was the first to show wound healing on day 14, which was not observed in the other two groups. c H&E staining. On day 14, the skin of the cryo-gel group had a thicker fat layer and complete skin appendages, whereas fat necrosis and thickened interstitial fibrous tissue were observed in the cutaneous fat layer in the other groups. n = 6 mice

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Stem Cell Research & Therapy

ISSN: 1757-6512