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Table 1 Differential expression of markers on mesenchymal cells isolated from different sources

From: An overview on small molecule-induced differentiation of mesenchymal stem cells into beta cells for diabetic therapy

Type Source of MSC Positive expression Negative expression Beta cell differentiation reported Reference
Adult tissues derived Peripheral blood CD105, CD90, CD73, CD73, CD44, CD90.1, CD29, CD105, CD106, CD140α CD34, CD19, CD11b No [26]
Bone marrow CD105, CD13, CD140b, CD147, CD151, CD276, CD29, CD44, CD47, CD59, CD73, CD81, CD90, CD98 CD14, CD31, CD34, CD45 Yes [27]
Skin/foreskin CD29, CD44, CD73, CD90, CD105, vimentin CD34, CD45, HLADR No [28]
Adipose CD9, CD29, CD44, CD54, CD73, CD90, CD105, CD106, CD146, CD166 CD14, CD31, CD34, CD45, CD133, CD144, HLA-DR, STRO-1 Yes [29]
Urine CD29, CD44, CD54, CD73, CD90, CD105, CD166, STRO-1, Oct-4, Klf-4, Sox-17, vimentin CD41, HLA-DR Yes [30, 31]
Heart CD44, CD105, CD29, CD90 CD14, CD45, CD34, CD31 No [32]
Dental CD13, CD29, CD44, CD49, CD73, CD90, CD146, STRO-1, Oct-3/4, NANOG, SSEA-3 CD14, CD31, CD34, CD45, HLADR Yes [33, 34]
Skeletal muscle CD29, CD44, CD49E, CD56, CD73, CD90, CD105, HLA-I CD34, CD45 No [35]
Pancreas CD105, CD90, CD73, CD44, CD29, CD13, nestin, vimentin, CD146, NG2, α-SMA, PDGF-R β CD31, CD34, and CD45, CK19, CA19.9 Yes [36]
Lung CD73, CD90, and CD105, vimentin, prolyl-4-hydroxylase CD14, CD34, CD45 No [37]
Pluripotent stem cell derived ESC CD29, CD44, CD73, CD105, SSEA-4, CD34, CD45, HLADR No [38]
iPSC CD29, CD44, CD166, CD73, CD105, KDR, MSX2 CD34, CD45, HLADR No [39]
Birth related tissue derived Wharton jelly CD44, CD73, CD90, CD105, CD166 CD14, CD34, CD45 Yes [40]
Placenta CD105, CD73, CD90c-kit, Thy-1, Oct-4, SOX2, hTERT, SSEA-1,3,4, TRA-1 CD34, CD45, CD14 or CD11b, CD19, HLA-DR Yes [41, 42]
Umbilical cord CD73, CD90, CD105, Oct-4, Nanog, ABCG2, Sox-2, Nestin CD34, CD45, CD19, HLA-DR Yes [43, 44]
Chorionic villi CD44, CD117, CD105, α-SMA, CD49, CD146, CD106, CD166, Stro-1, vWF CD34, CD45, CD19, HLA-DR No [45]
Chorionic membrane CD44, CD49, CD56, CD73, CD90, CD105 CD45, CD34, CD14, CD31, EPCAM, HLA-DR No [45]
Cord blood CD29, CD 73, CD105, CD44, Oct-4, Sox-1, Sox2, NANOG, ABCG2, Nestin CD34, CD45 Yes [44]
Limb bud CD13, CD29, CD44, CD90, CD105, CD106, SCA1, Runx2, SOX 9 CD3, CD5, CD11b, CD14, CD15, CD34, CD45, CD45RA, HLA-DR No [46, 47]
Endometrium CD73, CD90, CD105, CD166, HLA-ABC, Oct-4, CD14, CD34, CD45, HLA-DR No [48]
Amniotic membrane CD73, CD90, CD105, Oct-4, SSEA-4, Tra-1 CD11b, CD14, CD19, CD79α, CD34, CD45, HLA-DR No [49, 50]
Amniotic fluid CD73, CD90, CD105, CD166, MHC class I, Oct-4, EA-1 CD 45, CD40, CD34, CD14, HLA-DR Yes [51]