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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Intervention for early diabetic nephropathy by mesenchymal stem cells in a preclinical nonhuman primate model

Fig. 2

Fluorescence microscopy of MSCs in rhesus macaques. MSCs were labeled by CM-Dil (red fluorescence) before infusion to rhesus macaques. a Renal biopsies at 1 week and 1 month after MSC transplantation. b Immunostaining of kidney tissues at 1 month after MSC transplantation. c Quantification of number of MSCs per field at 1 week and 1 month after MSCs infusion. MSCs were labeled by CM-Dil (red), tubular epithelial cells were stained by E-cadherin (green), and cell nuclei were stained by Hoechst (blue). Scale bar of a = 10 μm and scale bar of b = 20 μm. Each bar represents the mean ± s.e.m. Four fields of each section, four sections per rhesus macaque were observed and quantified, and the number of rhesus macaques was analyzed in each group: Normal (n = 3), DN + NS (n = 4), DN + MSCs (n = 8)

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Stem Cell Research & Therapy

ISSN: 1757-6512