Fig. 4

Proliferation assay of OA and RA iPSC (a) RT PCR data expressed as mRNA levels of markers related to salvage pathways. b Immunofluorescence assay of NMNAT3. c CCK-8 assay of OA and RA iPSCs expressed as the difference of proliferation. d CCK-8 assay of OA and RA iPSCs showing the difference of proliferation after treatment with tannic acid (TA), inhibitor of NMNAT3. e CCK-8 assay data of OA iPSCs after treatment with TA. f CCK-8 assay data of RA iPSCs after treatment with TA. g CCK-8 assay of OA and RA iPSCs showing some difference of proliferation after treatment with STF-118804, inhibitor of NAMPT. h CCK-8 assay data of OA iPSCs after treatment with STF. i CCK-8 assay data of RA iPSCs after treatment with STF. Data presented mean ± SEM. All data was analyzed by the Student t test. *p < 0.05, **p < 0.01, ***p < 0.001