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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Dimethyloxaloylglycine-stimulated human bone marrow mesenchymal stem cell-derived exosomes enhance bone regeneration through angiogenesis by targeting the AKT/mTOR pathway

Fig. 4

Mechanism of proangiogenic effects of DMOG-MSC-Exos. a HUVECs were treated with MSC-Exos with or without DMOG, treated with PBS as the control, mRNA levels of p53, p21, p65, Hippo-YAP, JAK-STAT, β-catenin, and PTEN were evaluated by qRT-PCR. b HUVECs were treated with MSC-Exos, DMOG-MSC-Exos, and PBS as a control; protein levels of members of the AKT/mTOR pathway were detected by western blotting. Actin was used as a loading control (*P < 0.05, versus control; #P < 0.05, versus MSC-Exos)

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Stem Cell Research & Therapy

ISSN: 1757-6512