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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: TSG-6 in conditioned media from adipose mesenchymal stem cells protects against visual deficits in mild traumatic brain injury model through neurovascular modulation

Fig. 7

Depletion of TSG-6 from ASC-CCM fails to improve inflammatory gene expression in the retina of blast injury mice. a The RNA was isolated and analyzed by NanoString neuropathology gene panel. Heat map showing hierarchical clustering of genes upregulated (red) or downregulated (green) in retinal tissues from sham blast mice (sham), blast injury mice that received intravitreal saline (Blast-sal), blast injury mice that received primed siControl ASC-CCM (Blast-C), and blast injury mice that received primed siTSG-6-ASC-CCM (Blast-T) (n = 4–9 per group). b TaqMan gene expression analysis of representative genes selected from NanoString multiplex RNA analysis from all study groups (n = 4–9 per group). *p < 0.05; **p < 0.01; ***p < 0.001; #p > 0.05

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