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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: CD51 distinguishes a subpopulation of bone marrow mesenchymal stem cells with distinct migratory potential: a novel cell-based strategy to treat acute myocardial infarction in mice

Fig. 7

CD51+bMSC therapy attenuated inflammatory responses in the hearts after MI. a Immunofluorescence staining of IL-1β (red) in the border areas of the heart sections from the CD51−bMSC- and CD51+bMSC-treated mice at day 3 after MI. DAPI was used to stain the nuclei. Scale bars are marked in the figure. b Quantification of IL-1β-positive cells is presented as the percentage per high power field (Hpf) (n = 5). c Representative images of IL-1β expression was determined by flow cytometry in the hearts from cell-treated mice on day 3 after MI. Red histogram is the negative control. The left side of the green histogram (in the negative control part) represents the negative expression of IL-1β marker; the right side represents the positive expression of IL-1β marker. d Measurement of IL-1β-positive cells is presented as the percentage of the total cells in the injured ventricle on day 3 after MI (n = 3). Data in all panels are presented as the mean ± SD, *P < 0.05, **P < 0.01

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Stem Cell Research & Therapy

ISSN: 1757-6512