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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Microtubule destabilization caused by silicate via HDAC6 activation contributes to autophagic dysfunction in bone mesenchymal stem cells

Fig. 5

High concentration of silicate did not affect the expression of autophagosome-lysosome fusion related proteins of BMSCs. a, b Autophagosome-lysosome fusion-related proteins including SNAP29, STX17, and VAMP8 were determined by Western blot (n = 4). There was no significant difference after exposure to different doses of silicate for 24 h. c RT-qPCR further confirmed that there was no significant difference in the gene expression of SNAP29, STX17, and VAMP8 between groups (n = 4). (ns: no significance)

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Stem Cell Research & Therapy

ISSN: 1757-6512