Fig. 5

Effects of ASC-CM on rat wound healing rate. a Experimental procedure. b Overall morphological changes observed during the wound healing. c Changes in wound area during healing. Note that the fastest wound healing rate and the smallest wound area occurred in the ASC-CM group compared to other three control groups; MSC-CM, mesenchymal stem cell-conditioned medium; ASC-CM, antler stem cell-conditioned medium; n = 8/group; ^*p < 0.05, ^**p < 0.01, ^***p < 0.001 compared to DMEM; ^#p < 0.05, ^##p < 0.01, ^###p < 0.001 compared to EGF; bar = 5 mm; mean ± SD