Fig. 5
From: Immunomodulatory effects of interferon-γ on human fetal cardiac mesenchymal stromal cells
hfcMSCs induce T cell death via contact-dependent mechanisms. Levels of apoptosis and total cell death were assessed in CD3+ T cells co-cultured with hfcMSCs in contact and transwell systems. a Representative contour plots demonstrating the shift in CD3+ T cell viability and percentage of pre-apoptotic (Annexin V+ LIVE/DEAD®-), apoptotic (Annexin V+ LIVE DEAD®+), and total dead (LIVE DEAD®+) cells in control, contact, and transwell co-cultures. b Bar graph illustrating average percentage pre-apoptotic, apoptotic, and dead CD3+ T cells ± SEM (n = 4 hfcMSC donors). *P < 0.05