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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Protective properties of heme oxygenase-1 expressed in umbilical cord mesenchymal stem cells help restore the ovarian function of premature ovarian failure mice through activating the JNK/Bcl-2 signal pathway-regulated autophagy and upregulating the circulating of CD8+CD28− T cells

Fig. 5

HO-1, Bcl-2, and autophagy-related mRNA expression in ovarian tissues by QRT-PCR. a-1–a-3 HO-1 mRNA expression. b-1–b-3 Bcl-2 mRNA expression. c-1–c-3 LC3II/I mRNA expression. d-1–d-3 p62 mRNA expression. e-1–e-3 beclin1 mRNA expression. f-1–f-3 Atg5 mRNA expression. *P < 0.05, **P < 0.01, ***P < 0.001 vs DMSO, GC group, or NC group, separately. DMSO, dimethylsulfoxide; HO-1, heme oxygenase-1; NC, empty vector; POF, premature ovarian failure; UCMSCs, umbilical cord mesenchymal stem cells

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Stem Cell Research & Therapy

ISSN: 1757-6512