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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter

Fig. 2

Cell populations and GO enrichment analysis of unsorted chondroprogenitor cells. a scRNA-seq identified unsorted chondroprogenitor cells contained at least 9 populations, which could be further categorized into 3 broad classes: neurogenic cells (blue dashed circle), chondrogenic cells (green dashed circle), and mesenchyme (brown dashed circle). b Expression of signature genes of each cell lineage. c GO terms analysis (biological process) of each unique population. d Percentage of total unsorted chondroprogenitor cells in each unique cell population. More than 20% of the unsorted chondroprogenitors were SOX2/TTR/NES+ neurogenic cells, while only small number of unsorted cells expressed SOX9 and COL2A1. See also Figure S1

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Stem Cell Research & Therapy

ISSN: 1757-6512