Fig. 6

hiPSC-PRE suppressed the microglial activation and ameliorated the ocular environment condition in rd10. a Representative images of Western blot for CD68 and Bax. b Average protein expression of CD68 and Bax in rd10 mouse retina after hiPSC-RPE cell transplantation, retinas from non-transplantation rd10 mice, and WT at the same age are used for comparison. c Representative images of retinal immunohistochemistry for CD68. d Quantification of CD68-positive cell density. Scale bar 50 μm (c). Data are presented as mean ± SEM. p values were determined by one-way ANOVA followed by Tukey multiple comparison tests (b, d), n = 4 for each group, *p < 0.05, **p < 0.01