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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Mesenchymal stem cells regulate the Th17/Treg cell balance partly through hepatocyte growth factor in vitro

Fig. 5

The regulatory effect of HGF secreted by MSCs on neutrophil activities in cells cocultured with CD4+ T cells and analysed with flow cytometry. The results indicated that CD4+ T cells cocultured with MSCs significantly inhibited neutrophil phagocytic (p < 0.05, a) and oxidative burst activities (p < 0.01, b). However, the effects of the CD4+ T cells were inhibited by an anti-HGF antibody (p < 0.05 or p < 0.01) (n = 3; *p < 0.05 or **p < 0.01 vs. the CD4+ group; #p < 0.05 or ##p < 0.01 vs. the MSC+CD4+ group). MSCs, mesenchymal stem cells; rmHGF, recombinant mouse hepatocyte growth factor

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Stem Cell Research & Therapy

ISSN: 1757-6512