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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Tumor necrosis factor α in aGVHD patients contributed to the impairment of recipient bone marrow MSC stemness and deficiency of their hematopoiesis-promotion capacity

Fig. 3

aGVHD MSCs are deficient in hematopoietic supporting capacity. a The morphologic characteristics of CFCs in long-term culture of hematopoietic cells were observed under an inverted light microscope. Bars in a represent 200 μm. b The CFC number in the different weeks and c the CFC number of the bulk culture of long-term culture-initiating cells were counted under an inverted light microscope. Less CFCs were generated in the presence of aGVHD MSCs. *p < 0.05, **p < 0.01, compared with non-aGVHD groups, n = 5

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