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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Treatment of vocal fold scarring with autologous bone marrow-derived human mesenchymal stromal cells—first phase I/II human clinical study

Fig. 3

Vocal fold recordings and analysis. (3a, 3b) Patient 1 with small scar defect on left vocal fold preoperative and 1 year postoperative (marked with asterisk). (3c) Patient 12, preoperative a small scar defect on right vocal fold (marked with two asterisks). (3d) Eight months after MSC treatment with restored vocal fold edge. (3e, 3f) Kymograms for patient 1 of vocal fold vibrations preoperative (top) and 12 months postoperative (bottom). Time scale to right. (3e) Incomplete glottal closure and reduced vibrations of the left vocal fold (lower) than right vocal fold (top). (3f) Complete glottal closure at 12 month follow-up. (3g, 3h) Kymograms for patient 12 preoperative with incomplete glottal closure and reduced vibrations (top) and 8 months postoperative with complete closure and more symmetric vocal fold vibrations (bottom). (3i) Patient 6 who has a larger defect anterior on the right vocal fold (arrow)

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