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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Administration of allogeneic mesenchymal stem cells in lengthening phase accelerates early bone consolidation in rat distraction osteogenesis model

Fig. 5

Representative histological images and the quantitative results of the distraction regenerate in the DO animals. Animals were treated with single injection of MSCs on day 3 (D3), day 6 (D6), or day 10 (D10), or one injection of MSCs on day 3, day 6, and day 10 (triple). a Samples were stained with H&E, Safranin O & Fast Green (SO & FG), or immunohistochemical staining with osteocalcin expression (OCN). Arrows indicate the unmineralized tissue. Data were shown as mean ± SD (n = 8). b Quantitative results of unmineralized tissue per DO regenerate. c Quantitative results of OCN-positive expressing tissue area per DO regenerate. *p < 0.05, **p < 0.01, ***p < 0.001 vs. CON

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