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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Autophagy modulation altered differentiation capacity of CD146+ cells toward endothelial cells, pericytes, and cardiomyocytes

Fig. 1

Schematic illustration of study design (a). MTT assay (b); Measuring CD146+ cell survival rate by MTT assay after exposure to different doses of HCQ (n = 16). Our data illustrated that 15-μM HCQ is the optimum dose for autophagy inhibition in CD146+ cells with a minimal toxic effect. LysoTracker Green staining (ce). Fluorescence microscopy imaging confirmed that 15-μM HCQ inhibited autophagic flux (c, d (n = 100 cells) and e (n = 100 cells)). Data are expressed as mean ± SD. One-way ANOVA and Tukey post hoc test. *p < 0.05; **p < 0.01

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