Skip to main content
Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Mesenchymal stem cells combined with liraglutide relieve acute lung injury through apoptotic signaling restrained by PKA/β-catenin

Fig. 8

Schematic showing the regulation of apoptosis in MSCs through the PKA/β-catenin pathway. Liraglutide stimulated the expression of PKA by targeting GLP-1R and then motivated the expression of β-catenin, thereby attenuating the expression of Bax, cleaved caspase-9, and cleaved caspase-3 and enhancing the expression of Bcl-2, consequently reducing the apoptosis of MSCs

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512