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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: LncRNA H19 promotes odontoblastic differentiation of human dental pulp stem cells by regulating miR-140-5p and BMP-2/FGF9

Fig. 6

Overexpression of miR-140-5p reversed the stimulation effect of H19 in vitro. a Relative RNA expression of mineralization-related genes in the miR-140-5p co-transfection experiment after odontoblast induction for 14 days. b Relative protein expression of RUNX2, DSPP, and DMP-1 in the miR-140-5p co-transfection experiment after odontoblast induction for 14 days. c Images of Alizarin Red S staining in the miR-140-5p co-transfection experiment. hDPSCs were cultured in odontoblastic medium for 14 days. Histograms revealed quantification of Alizarin Red S staining by spectrophotometry. d The schematic diagram for lncRNA-H19/miR-140-5p/BMP-2/FGF9 axis. The data are presented as the mean ± SD in three independent experiments. *P < 0.05, **P < 0.01

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Stem Cell Research & Therapy

ISSN: 1757-6512