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Table 2 SYRCLE Risk of Bias Assessment for included studies

From: Efficacy of mesenchymal stem cell therapy for sepsis: a meta-analysis of preclinical studies

Author (Year)

Random sequence generation?

Groups similar at baseline?

Allocation concealed?

Animals randomly housed?

Blinding of caregivers and/or examiners?

Random selection for outcome assessment?

Blinding of outcome assessor?

Incomplete outcome data addressed?

Free from selective outcome reporting?

Free from other bias?

Gonzalez-Rey et al.(2009) [10]

U

U

U

U

U

U

U

L

L

H

Nemeth et al. (2009) [11]

U

U

U

U

U

U

U

L

L

L

Bi et al. (2010) [12]

U

U

U

U

U

U

U

H

L

L

Mei et al. (2010) [13]

U

U

U

U

U

U

U

L

L

H

Liang et al. (2011) [14]

U

U

U

U

U

U

U

U

L

L

Chang et al. (2012) [15]

U

U

U

U

U

U

U

U

L

H

Krasnodembskaya et al.(2012) [16]

U

U

U

U

U

U

U

U

L

L

Li et al. (2012) [17]

U

U

U

U

U

U

U

U

L

L

Hall et al. (2013) [18]

U

U

U

U

U

U

U

U

L

L

Zhao et al. (2013) [19]

U

U

U

U

U

U

U

U

L

L

Chao et al. (2014) [20]

U

U

U

U

U

U

U

U

L

L

Kim et al. (2014) [21]

U

U

U

U

U

U

H

U

L

L

Luo et al. (2014) [22]

U

U

U

U

U

U

U

U

L

L

Pedrazza et al. (2014) [23]

U

U

U

U

U

U

U

U

L

L

Sepulveda 2014 [24]

U

U

U

U

U

U

U

U

L

L

Zhao et al. (2014) [25]

U

U

U

U

U

U

U

U

L

L

Zhou et al. (2014) [26]

U

U

U

U

U

U

U

H

L

L

Yang et al. (2015) [28]

U

U

U

U

U

U

U

U

L

L

Francisca et al. (2015) [27]

U

U

U

U

U

U

U

L

L

L

Hao Ou et al. (2015) [29]

U

U

U

U

U

U

U

L

L

L

Pei-Hsun Sung et al. (2017) [30]

U

U

U

U

U

U

U

L

L

L

Xujing Liang et al. (2019) [33]

U

U

U

U

U

U

U

L

L

L

Xian-Fei Ding et al. (2019) [31]

U

U

U

U

U

U

U

L

L

L

Mirjana Jerkic et al. (2019) [32]

U

U

U

U

U

U

U

U

U

U

Huoyan Liang et al. (2019) [41]

U

U

U

U

U

U

U

L

L

L

  1. H High risk of bias, L Low risk of bias, U Unclear risk of bias