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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: FNDC5/irisin improves the therapeutic efficacy of bone marrow-derived mesenchymal stem cells for myocardial infarction

Fig. 6

Evaluation of fibrosis, pro-angiogenic effect, and heart function after different groups. a Masson’s trichrome staining indicated left ventricular fibrosis 4 weeks after various treatments (magnification × 4). b Representative quantitative analysis of the fibrotic area. c Capillaries in the infarct border zone were determined by immunohistochemical staining for CD31-positive cells in different groups (scale bars = 50 μm). d Representative capillaries in the infarct border zone. Histograms illustrating the heart function parameters: left ventricular end-diastolic diameter (LVEDD, e), left ventricular end-systolic diameter (LVESD, f), left ventricular fractional shortening (g), and left ventricular ejection fraction (h). Data are expressed as means ± SEM; n = 5; *p < 0.05

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