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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: miR-132-3p priming enhances the effects of mesenchymal stromal cell-derived exosomes on ameliorating brain ischemic injury

Fig. 4

miR-132-3p priming enhanced the effects of MSC-EXs on decreasing ROS production and apoptosis of H/R-injured ECs via activating the PI3K/Akt/eNOS pathway. ac Representative bands and summarized data showing the protein level of p-Akt/Akt and p-eNOS/eNOS in ECs. d, f Representative images and summarized data showing the ROS production of ECs treated by various MSC-EXs and PI3K inhibitor (LY294002), scale bar = 100 μm. e, g Representative images and summarized data showing the apoptosis of ECs treated by various MSC-EXs and PI3K inhibitor (LY294002). *p < 0.05; n = 3/group

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