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Table 1 Clinical features of patients in two groups before treatment

From: HLA-mismatched GPBSC infusion therapy in refractory Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis: an observational study from a single center

Clinical features

No. of patients

p valve

Infusion group (n = 18)

Control group (n = 19)

Median age, years

21 [11–60]

29 [17–57]

0.368

Gender, female to male

5:13

6:13

0.800

Fever

18 (100%)

19 (100%)

Splenomegaly/hepatomegaly

16 (88.9%)

16 (84.2%)

0.677

Hemophagocytosis

14 (77.8%)

14 (73.7%)

0.772

NK cell activity < 15.11%

6 (33.3%)

4 (21.1%)

0.401

soluble CD25 > 6400 pg/ml

14 (77.8%)

19 (100%)

0.100

EBV-DNA (copies/ml) (at diagnosis)

5.0 × 105 [1.5 × 103, 7.7 × 107]

1.0 × 106 [2.0 × 103, 5.2 × 107]

0.090