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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Nonadherent culture method promotes MSC-mediated vascularization in myocardial infarction via miR-519d/VEGFA pathway

Fig. 4

VEGFA secretion by VEGFA-overexpressing AC-hMSCs improves cardiac functions in a rat MI model. a Cardiac function was determined by echocardiography 28 days after MI induction and hMSC transplantation. b Quantification of LVEDD, c LVESD, d LVEF, and e LVFS. Data are represented as mean ± SD (n = 8 per group). ∗P < 0.05 compared to AC-hMSC-Ctrl or nonAC-hMSC-NC group. #P < 0.05 compared to MI group. ▲P < 0.05 compared to AC-hMSC-Ctrl group

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Stem Cell Research & Therapy

ISSN: 1757-6512