Fig. 3From: Protective effect of miRNA-containing extracellular vesicles derived from mesenchymal stromal cells of old rats on renal function in chronic kidney diseaseRepresentative micrographs of tubulointerstitial injury in the obstructed kidney after UUO in different experimental groups (HE staining of rats’ kidney sections, × 200). a Young and old rats were subjected to unilateral ureteral obstruction (UUO), and HE was used to analyse the histological changes of young or old MSC-EVs treatment at 7 and 14 days after surgery. b Young and old rats were subjected to unilateral ureteral obstruction (UUO), and HE was used to analyse the histological changes of LV-miR-294/133 inhibitor/mimic treatment at an end point of 7 and 14 days after surgery. c–e The quantitative analysis results of tubulointerstitial injury in the kidneys. All data are represented as the mean ± SE. The rat number in each group is 5. *p < 0.05 compared with the UUO groupBack to article page