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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Protective effect of miRNA-containing extracellular vesicles derived from mesenchymal stromal cells of old rats on renal function in chronic kidney disease

Fig. 3

Representative micrographs of tubulointerstitial injury in the obstructed kidney after UUO in different experimental groups (HE staining of rats’ kidney sections, × 200). a Young and old rats were subjected to unilateral ureteral obstruction (UUO), and HE was used to analyse the histological changes of young or old MSC-EVs treatment at 7 and 14 days after surgery. b Young and old rats were subjected to unilateral ureteral obstruction (UUO), and HE was used to analyse the histological changes of LV-miR-294/133 inhibitor/mimic treatment at an end point of 7 and 14 days after surgery. c–e The quantitative analysis results of tubulointerstitial injury in the kidneys. All data are represented as the mean ± SE. The rat number in each group is 5. *p < 0.05 compared with the UUO group

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