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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Human amnion mesenchymal stem cells restore spermatogenesis in mice with busulfan-induced testis toxicity by inhibiting apoptosis and oxidative stress

Fig. 5

hAMSCs repressed oxidative damage and augmented oxidative defense in Sertoli cells with busulfan administration. a A schematic diagram of hAMSCs (on the upper coculture inserts) cocultured with mouse Sertoli cells (on the bottom of a 6-well culture plate). b The percentage of ROS+/Annexin V+ Sertoli cells was analyzed by FACS in the three groups. c–h The expression of LDH, MDA, GR, SOD, GPx, and CAT was determined by ELISA analysis in three groups. The results are presented as the mean ± SD. ***p < 0.001 (compared to the BSF group)

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Stem Cell Research & Therapy

ISSN: 1757-6512