Fig. 6From: Prophylactic therapy with human amniotic fluid stem cells improved survival in a rat model of lipopolysaccharide-induced neonatal sepsis through immunomodulation via aggregates with peritoneal macrophageshAFSCs regulated immune reaction by two steps: peritoneal macrophages and spleen. hAFSCs regulated immune reaction in the whole body by two steps—phenotypic switch of peritoneal macrophages from M1 to M2 and the immune reactions of the spleen following the phenotypic switch of peritoneal macrophagesBack to article page