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Table 1 The optimal timing of hAFSC administration for eliciting significant therapeutic effect in LPS-induced neonatal sepsis

From: Prophylactic therapy with human amniotic fluid stem cells improved survival in a rat model of lipopolysaccharide-induced neonatal sepsis through immunomodulation via aggregates with peritoneal macrophages

Timing of hAFSC injection

Survival rate (%)

N

p value

LPS only

50.0

40

–

− 3 h

78.5

28

0.015*

0

56.3

16

0.67

+ 3 h

50.0

18

1.00

+ 24 h

50.0

20

1.00

  1. The chi-squared test between the LPS only and each of the other groups
  2. *p < 0.05